SCHEMBL26488187

SCHEMBL26488187

CCCCCCCCCCN(CCCCCCCCCC)C(c1ccco1)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.40
MEN1 O00255 4/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
THRA P10827 2/20 0.36
THRB P10828 2/20 0.36
ALOX5 P09917 1/20 0.35
NPSR1 Q6W5P4 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MAPT P10636 3/20 0.34
HTT P42858 2/20 0.34
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
RECQL P46063 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN7 P35236 1/20 0.33
BLM P54132 1/20 0.33
ESR2 Q92731 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26488205 1.00 KMT2A (0.40) KMT2AMEN1L3MBTL1THRATHRB
SCHEMBL26488210 0.78 KMT2A (0.38) KMT2AMEN1L3MBTL1THRATHRB
SCHEMBL26488189 0.75 L3MBTL1 (0.45) KMT2AMEN1L3MBTL1THRATHRB
SCHEMBL5613043 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL22127720 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL8716342 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL2828919 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL20773076 0.73 KMT2A (0.52) KMT2AMEN1L3MBTL1ALDH1A1MAPT
SCHEMBL26488234 0.72 ALOX5 (0.36) THRATHRBALOX5NPSR1ALDH1A1
SCHEMBL2139138 0.71 KMT2A (0.50) KMT2AMEN1L3MBTL1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS PHOSPHO1, SGMS1, PLIN3 KMT2A 3097/4885MEN1 3607/4885L3MBTL1 631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.