SCHEMBL26488189

SCHEMBL26488189

CCCCCCCCN(CCCCCCCC)C(C(=O)O)c1ccco1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
PKM P14618 2/20 0.42
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN7 P35236 1/20 0.42
BLM P54132 1/20 0.42
ESR2 Q92731 1/20 0.42
ALDH1A1 P00352 4/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
HTT P42858 1/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.41
RECQL P46063 1/20 0.41
NPC1 O15118 1/20 0.40
JAK2 O60674 1/20 0.40
RAB9A P51151 1/20 0.40
PAX8 Q06710 1/20 0.40
CYP2C19 P33261 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26488210 0.77 KMT2A (0.38) L3MBTL1KMT2AALDH1A1MAPTNPSR1
SCHEMBL26488187 0.75 KMT2A (0.40) L3MBTL1PKMKMT2APOLBPTPN1
SCHEMBL26488205 0.75 KMT2A (0.40) L3MBTL1PKMKMT2APOLBPTPN1
SCHEMBL26488286 0.75 GPR84 (0.39) ALDH1A1MAPTNPC1JAK2RAB9A
SCHEMBL26488291 0.75 GPR84 (0.39) ALDH1A1MAPTNPC1JAK2RAB9A
SCHEMBL11847308 0.75 KMT2A (0.46) L3MBTL1PKMKMT2APOLBPTPN1
SCHEMBL26488237 0.73 HDAC1 (0.40) L3MBTL1KMT2APOLBNPSR1HTT
SCHEMBL19097833 0.70 ALDH1A1 (0.42) L3MBTL1PKMKMT2APOLBPTPN1
SCHEMBL30264728 0.70 KMT2A (0.42) L3MBTL1PKMKMT2APOLBPTPN1
SCHEMBL19963545 0.69 L3MBTL1 (0.42) L3MBTL1PKMKMT2APOLBPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS PHOSPHO1, SGMS1, PLIN3 L3MBTL1 631/4885PKM 2178/4885KMT2A 3097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.