SCHEMBL26488286

SCHEMBL26488286

CCCCCCCCN(CCCCCCCC)C(C(=O)O)c1cc(C(C(=O)O)N(CCCCCCCC)CCCCCCCC)cc(C(C(=O)O)N(CCCCCCCC)CCCCCCCC)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.39
FFAR1 O14842 1/20 0.39
NPC1 O15118 1/20 0.39
JAK2 O60674 1/20 0.39
RAB9A P51151 1/20 0.39
PAX8 Q06710 1/20 0.39
NOD1 Q9Y239 2/20 0.39
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
ICMT O60725 1/20 0.37
ALB P02768 1/20 0.37
HCAR2 Q8TDS4 1/20 0.36
ALDH1A1 P00352 2/20 0.36
ASAH1 Q13510 1/20 0.36
ACER2 Q5QJU3 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
PLA2G2A P14555 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26488291 1.00 GPR84 (0.39) GPR84FFAR1NPC1JAK2RAB9A
SCHEMBL26488189 0.75 L3MBTL1 (0.45) NPC1JAK2RAB9APAX8MAPT
SCHEMBL8800957 0.75 ALDH1A1 (0.34) MAPTALDH1A1
SCHEMBL26488237 0.74 HDAC1 (0.40) NPC1JAK2RAB9APAX8ICMT
SCHEMBL9839518 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL11137702 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL28856639 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL9839621 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7770712 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7770709 0.72 ACE2 (0.46) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS SunVax mRNA Therapeutics Inc. (US) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322689-A1 IONIZABLE LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS PHOSPHO1, SGMS1, PLIN3 GPR84 3065/4885FFAR1 1736/4885NPC1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.