Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | LPL | P06858 | 8/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2180601 | 0.87 | HCAR3 (0.48) | DGAT1LPLLIPGAAK1CA1 | |
| SCHEMBL18436775 | 0.84 | DGAT1 (0.44) | DGAT1LPLLIPGAAK1USP30 | |
| SCHEMBL26484932 | 0.82 | AAK1 (0.38) | DGAT1LPLLIPGAAK1USP30 | |
| SCHEMBL2432651 | 0.82 | LPL (0.50) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL19996746 | 0.78 | DGAT1 (0.43) | DGAT1LPLLIPGUSP30CA1 | |
| SCHEMBL182973 | 0.78 | DGAT1 (0.46) | DGAT1LPLLIPGUSP30CA1 | |
| SCHEMBL22674352 | 0.78 | DGAT1 (0.43) | DGAT1LPLLIPGUSP30CA1 | |
| SCHEMBL182754 | 0.77 | DGAT1 (0.46) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL30059627 | 0.77 | DGAT1 (0.46) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL20894366 | 0.76 | HCAR3 (0.50) | DGAT1LPLLIPGUSP30CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072248-A1 | PYRIDYL-CONTAINING COMPOUND | 正大天晴药业集团股份有限公司 | 2023-05-04 | — | — | WO | disclosed |