Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 18/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648548 | 0.91 | MAPT (0.51) | GCGRKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL2647286 | 0.88 | GCGR (0.79) | GCGR | |
| SCHEMBL2648108 | 0.84 | MAPT (0.45) | GCGRKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL2648932 | 0.81 | GCGR (0.48) | GCGRMAPT | |
| SCHEMBL2649345 | 0.80 | GCGR (0.67) | GCGRKDM4EMAPTSLC10A2 | |
| SCHEMBL2648083 | 0.80 | MAPT (0.41) | GCGRKDM4EMEN1HSP90AA1MAPT | |
| SCHEMBL2648313 | 0.79 | GCGR (0.65) | GCGR | |
| SCHEMBL9268564 | 0.78 | GCGR (0.64) | GCGR | |
| SCHEMBL2648212 | 0.78 | GCGR (0.62) | GCGRKDM4EMEN1MAPTKMT2A | |
| SCHEMBL2648326 | 0.77 | GCGR (0.66) | GCGRMEN1MAPTKMT2ASLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |