Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662913 | 0.86 | GCGR (0.65) | GCGR | |
| SCHEMBL2648110 | 0.84 | LDHA (0.40) | LDHAALDH1A1L3MBTL1MAPT | |
| SCHEMBL2648931 | 0.81 | GCGR (0.61) | GCGRMAPT | |
| SCHEMBL2648085 | 0.81 | LDHA (0.37) | LDHAALDH1A1L3MBTL1MAPT | |
| SCHEMBL2649941 | 0.81 | GCGR (0.73) | GCGR | |
| SCHEMBL11010734 | 0.77 | ALDH1A1 (0.60) | LDHAALDH1A1L3MBTL1MAPT | |
| SCHEMBL2647286 | 0.77 | GCGR (0.79) | GCGR | |
| SCHEMBL10746812 | 0.74 | ALDH1A1 (0.53) | LDHAALDH1A1L3MBTL1MAPT | |
| SCHEMBL2647828 | 0.74 | MAPT (0.46) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2648375 | 0.73 | MAPT (0.43) | ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218431-B1 | GLUCAGON RECEPTOR ANTAGONISTS FOR THERAPY OF DIABETES AND CONDITIONS ASSOCIATED WITH DIABETES | BAYER CORPORATION | 2001-04-17 | — | — | US | disclosed |