Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | FURIN | P09958 | 7/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
| ▸ | PCSK6 | P29122 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26542866 | 0.83 | SIRT2 (0.33) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL24642304 | 0.81 | ECE1 (0.36) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL24642922 | 0.81 | SIRT1 (0.34) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL24642558 | 0.81 | FAAH (0.34) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL24642472 | 0.80 | SIRT1 (0.32) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL26496179 | 0.79 | ECE1 (0.42) | FURINPRSS1PCSK6 | |
| SCHEMBL24642327 | 0.78 | SIRT2 (0.34) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL24642309 | 0.78 | GLO1 (0.37) | MMP3FURINPRSS1MMP9 | |
| SCHEMBL24642686 | 0.76 | ECE1 (0.36) | FURINPRSS1SIRT1SIRT6SIRT2 | |
| SCHEMBL26499410 | 0.76 | SIRT1 (0.37) | FURINPRSS1SIRT1SIRT6SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |