Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.97 |
| ▸ | LMNA | P02545 | 4/20 | 0.93 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iohexol SCHEMBL26501 | 0.99 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL8844889 | 0.99 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL31722694 | 0.99 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL37920 | 0.99 | CYP2C19 (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL22645199 | 0.97 | LMNA (0.97) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL22719758 | 0.96 | CYP2C19 (0.95) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iohexol SCHEMBL3666605 | 0.96 | CYP2C19 (0.95) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL21546 | 0.96 | LMNA (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL8845042 | 0.96 | LMNA (1.00) | CYP2C19HIF1ALMNAEGFRSRC | |
| Iodixanol SCHEMBL37712 | 0.96 | LMNA (1.00) | CYP2C19HIF1ALMNAEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729351-A4 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORP (US) | 1998-02-04 | — | — | EP | disclosed |
| EP-0729351-A1 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORPORATION (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995013796-A1 | VESICLES WITH CONTROLLED RELEASE OF ACTIVES | DEPOTECH CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |