Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845806 | 0.85 | MEN1 (0.79) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL21880197 | 0.83 | MAPT (0.65) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL21880198 | 0.83 | MAPT (0.65) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL26503521 | 0.82 | KMT2A (0.76) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL27546642 | 0.81 | EPHX2 (0.52) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL2610082 | 0.81 | MEN1 (0.74) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL19316158 | 0.81 | NPC1 (0.74) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL18061115 | 0.81 | FPR2 (0.73) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL20963255 | 0.81 | CA1 (0.57) | RAB9AMEN1KMT2ANPC1MAPT | |
| SCHEMBL27521318 | 0.81 | TRPA1 (0.52) | RAB9AMEN1KMT2ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321123-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LasB | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321123-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LasB | SERPINB1, LTA, TFPI | RAB9A 1244/4885MEN1 4644/4885KMT2A 4437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.