Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885280 | 0.82 | ACHE (0.46) | PPARDPTPN1ACHEALDH1A1TUBB4A | |
| SCHEMBL7814590 | 0.76 | ACHE (0.44) | PTPN1ACHEALDH1A1TUBB4ATUBB | |
| SCHEMBL11101046 | 0.75 | ACHE (0.58) | PTPN1CYP3A4ACHEALDH1A1TUBB4A | |
| SCHEMBL5783392 | 0.74 | PTPN1 (0.40) | PPARDPTPN1PPARGALOX5ACHE | |
| SCHEMBL5785856 | 0.73 | PTPN1 (0.39) | PPARDPTPN1CYP3A4PPARGALOX5 | |
| SCHEMBL3690573 | 0.73 | PPARG (0.64) | PPARDPTPN1CYP3A4PPARGALOX5 | |
| SCHEMBL7195739 | 0.71 | ABL1 (0.50) | CYP3A4APPALOX5IGF1RRPS6KA3 | |
| SCHEMBL18288113 | 0.70 | ALDH1A1 (0.58) | ACHEALDH1A1 | |
| SCHEMBL15372462 | 0.70 | TUBB4A (0.56) | PPARDPTPN1CYP3A4PPARGALOX5 | |
| SCHEMBL13414990 | 0.69 | ACHE (0.54) | PTPN1CYP3A4ACHEALDH1A1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |