Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.50 |
| ▸ | MMP12 | P39900 | 8/20 | 0.50 |
| ▸ | MMP13 | P45452 | 8/20 | 0.50 |
| ▸ | MMP14 | P50281 | 8/20 | 0.50 |
| ▸ | MMP9 | P14780 | 7/20 | 0.50 |
| ▸ | MMP1 | P03956 | 6/20 | 0.50 |
| ▸ | MMP3 | P08254 | 6/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MMP16 | P51512 | 5/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014583 | 0.79 | COMT (0.44) | PTGDR2CTSBCA12CA1CA2 | |
| SCHEMBL8230938 | 0.79 | LOXL2 (0.43) | MMP13MMP1MMP8PTGDR2CTSB | |
| SCHEMBL8254703 | 0.78 | CTSB (0.43) | MMP2MMP12MMP13MMP14MMP9 | |
| Hydrochloric Acid SCHEMBL4611724 | 0.78 | LOXL2 (0.42) | MMP13MMP1MMP8PTGDR2CTSB | |
| Hydrochloric Acid SCHEMBL5003352 | 0.77 | CTSB (0.42) | MMP2MMP12MMP13MMP14MMP9 | |
| SCHEMBL8254111 | 0.76 | LOXL2 (0.46) | PTGDR2CTSBCA12CA1CA2 | |
| SCHEMBL1016972 | 0.76 | CTSB (0.42) | PTGDR2TDP1CTSBCA12CA1 | |
| SCHEMBL9988286 | 0.76 | CTSB (0.42) | PTGDR2CTSBCA12CA1CA2 | |
| SCHEMBL4599595 | 0.76 | TSHR (0.51) | MMP2MMP13MMP9MMP1MMP8 | |
| SCHEMBL1508334 | 0.74 | MMP2 (0.60) | MMP2MMP12MMP13MMP14MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2168962-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2010-03-31 | — | — | EP | disclosed |
| EP-1594867-B1 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LTD (GB) | 2008-04-09 | — | — | EP | disclosed |
| US-7214681-B2 | Tri(cyclo) substituted amide compounds | PROSIDION LIMITED (GB) | 2007-05-08 | — | — | US | disclosed |
| EP-1594867-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | Prosidion Limited (GB) | 2005-11-16 | — | — | EP | disclosed |
| US-20040181067-A1 | Tri(cyclo) substituted amide compounds | OSI PHARMACEUTICALS, INC. | 2004-09-16 | — | — | US | disclosed |
| WO-2004072031-A2 | PHENYLACETAMIDES AND THEIR USE AS GLUCOKINASE MODULATORS | PROSIDION LIMITED (GB) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040181067-A1 | Tri(cyclo) substituted amide compounds | GPR119, IAPP, SLC5A1 | MMP2 2394/4885MMP12 4420/4885MMP13 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.