SCHEMBL2651599

SCHEMBL2651599

O=C(Oc1ccccc1F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
PARP10 Q53GL7 1/20 0.42
CXCL8 P10145 1/20 0.42
ELANE P08246 2/20 0.42
KMT2A Q03164 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
GAA P10253 1/20 0.40
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
HPGD P15428 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28404237 0.87 ELANE (0.47) ALDH1A1SMN1; SMN2MAPTELANEKMT2A
SCHEMBL10181532 0.85 CES2 (0.42) PARP10CXCL8ELANEKMT2ACES1
SCHEMBL10182173 0.85 FAAH (0.42) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL24946068 0.83 FAAH (0.41) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL19335427 0.82 ELANE (0.62) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL10179777 0.81 TSHR (0.47) FAAHMAPTKMT2AL3MBTL1CES1
SCHEMBL10180573 0.81 CES2 (0.42) MAPTKMT2AL3MBTL1CES1CES2
SCHEMBL15495717 0.80 RIPK1 (0.48) FAAHALDH1A1SMN1; SMN2MAPTCXCL8
SCHEMBL2940941 0.79 FAAH (0.49) FAAHALDH1A1SMN1; SMN2MAPTPARP10
SCHEMBL18697277 0.79 FAAH (0.49) FAAHALDH1A1SMN1; SMN2MAPTPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
CN-102484281-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2012-05-30 CN disclosed
CN-1859912-A Inhibitors of Akt activity SMITHKLINE BEECHAM CORP (US) 2006-11-08 CN disclosed
WO-2002099141-A9 FLUORESCENT QUENCHING DETECTION REAGENTS AND METHODS EPOCH BIOSCIENCES INC (US) 2004-05-27 WO disclosed
WO-2002070469-A2 SELECTIVE PDE3B INHIBITORS AND USE OF THE SAME IN THERAPY ICOS CORPORATION (US) 2002-09-12 WO disclosed
EP-1183229-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2002-03-06 EP disclosed
EP-1173427-A1 HYDROXAMIC ACID DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2002-01-23 EP disclosed
WO-2000069810-A1 GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2000-11-23 WO disclosed
WO-2000063197-A1 HYDROXAMIC ACID DERIVATIVE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2000-10-26 WO disclosed
EP-0804466-A1 NOVEL TETRAPEPTIDES, THEIR MANUFACTURE AND USE BASF AKTIENGESELLSCHAFT (DE) 1997-11-05 EP disclosed
WO-1995030690-A1 NOVEL TETRAPEPTIDES, THEIR MANUFACTURE AND USE BASF AKTIENGESELLSCHAFT (DE) 1995-11-16 WO disclosed