SCHEMBL28404237

SCHEMBL28404237

O=C(Oc1ccccc1OC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.47
CES1 P23141 2/20 0.43
SERPINE1 P05121 1/20 0.39
GAA P10253 1/20 0.38
TP53 P04637 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
MLYCD O95822 1/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ESR1 P03372 1/20 0.36
ITGB3 P05106 1/20 0.36
ITGA2B P08514 1/20 0.36
HMGB1 P09429 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
GGT1 P19440 1/20 0.36
PTGS1 P23219 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2651599 0.87 FAAH (0.44) ELANECES1GAAALDH1A1MAPT
SCHEMBL30185696 0.86 FABP7 (0.44) ELANECES1GAAHDAC6MLYCD
SCHEMBL6838181 0.86 ELANE (0.44) ELANEMAPTKMT2ATDP1
SCHEMBL326468 0.86 FABP7 (0.44) ELANECES1GAAHDAC6MLYCD
SCHEMBL3693664 0.85 ELANE (0.39) ELANECES1KMT2A
SCHEMBL6446668 0.84 KDM4E (0.59) ELANEALDH1A1MAPTKMT2AKDM4E
SCHEMBL6851496 0.82 TDP1 (0.55) ELANEGAAALDH1A1KDM4ETSHR
SCHEMBL4082182 0.82 ALDH1A1 (0.56) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL9541871 0.82 FABP3 (0.49) ALDH1A1SMN1; SMN2KDM4ETDP1
SCHEMBL27361577 0.82 CTNNB1 (0.51) ELANEGAAHDAC6ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775300-A Synthesis method of azo silane coupling agent 山东阳谷华泰化工股份有限公司 2025-04-08 CN disclosed
CN-119775302-A Preparation method of structurally symmetrical azo silane coupling agent 山东阳谷华泰化工股份有限公司 2025-04-08 CN disclosed
CN-119775301-A Preparation method of azo silane coupling agent 山东阳谷华泰化工股份有限公司 2025-04-08 CN disclosed
CN-119775303-A Synthesis method of structurally symmetrical azo silane coupling agent 山东阳谷华泰化工股份有限公司 2025-04-08 CN disclosed
CN-107488155-B Preparation method of α -unsaturated gamma-lactone 北京工商大学 2020-06-09 CN disclosed