Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.57 |
| ▸ | GCGR | P47871 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230855 | 0.81 | MAOB (0.63) | MAOBMAOAKMT2AKDM4EALDH1A1 | |
| SCHEMBL2650140 | 0.79 | GCGR (0.59) | MAOBGCGRMAOAMEN1KMT2A | |
| SCHEMBL7229722 | 0.78 | GCGR (0.64) | GCGRMEN1KMT2ATDP1SIGMAR1 | |
| SCHEMBL2652406 | 0.77 | GCGR (0.61) | MAOBGCGRMAOAMEN1KMT2A | |
| SCHEMBL219973 | 0.74 | NOS3 (0.52) | MEN1KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL4040688 | 0.74 | ABCB1 (0.64) | MAOBMAOAABCB1 | |
| SCHEMBL4040694 | 0.74 | ABCB1 (0.77) | ABCB1 | |
| SCHEMBL7253739 | 0.73 | L3MBTL1 (0.64) | MAOBMAOAMEN1KMT2ATDP1 | |
| SCHEMBL7237603 | 0.73 | MET (0.44) | MAOBMAOA | |
| SCHEMBL3860629 | 0.72 | KDM4E (0.69) | MEN1KMT2ATDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |