Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652409 | 0.81 | MAOB (0.57) | MAOBMAOAALDH1A1KDM4EKMT2A | |
| SCHEMBL6107363 | 0.76 | MCHR1 (0.68) | HTR4MCHR1ALDH1A1LMNAPOLB | |
| SCHEMBL7230848 | 0.76 | MAOB (0.51) | MAOBMAOAALDH1A1KDM4EGAA | |
| SCHEMBL7237603 | 0.76 | MET (0.44) | MAOBMAOAMCHR1MET | |
| SCHEMBL4750836 | 0.75 | GAA (0.74) | ALDH1A1KDM4EGAAKMT2ALMNA | |
| SCHEMBL6109544 | 0.73 | MCHR1 (0.73) | MCHR1LMNAFAAHACHE | |
| SCHEMBL9815637 | 0.72 | LMNA (0.57) | ALDH1A1KDM4EGAALMNAHTT | |
| SCHEMBL6110834 | 0.72 | MCHR1 (0.74) | MCHR1LMNA | |
| SCHEMBL12259234 | 0.72 | ALDH1A1 (0.82) | MAOBMAOAALDH1A1KDM4EKMT2A | |
| SCHEMBL4939202 | 0.72 | TP53 (0.66) | ALDH1A1KDM4EGAAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |