SCHEMBL265259

SCHEMBL265259

Clc1cccc2nc3ccccc3nc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
MAPT P10636 2/20 0.56
RAB9A P51151 2/20 0.56
GAA P10253 1/20 0.56
KMT2A Q03164 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
NQO2 P16083 7/20 0.52
TDP1 Q9NUW8 1/20 0.50
ADORA3 P0DMS8 1/20 0.47
ADORA1 P30542 1/20 0.47
ACHE P22303 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487872 1.00 ALDH1A1 (0.56) ALDH1A1MAPTRAB9AGAAKMT2A
Hydrochloric Acid SCHEMBL28566743 0.98 MAPT (0.54) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL23589560 0.93 NQO2 (0.52) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL31558290 0.93 NQO2 (0.52) ALDH1A1MAPTRAB9AGAAKMT2A
Maleic Acid SCHEMBL28811648 0.84 ALDH1A1 (0.53) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL28411484 0.83 ALDH1A1 (0.49) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL7527351 0.81 TDP1 (0.56) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL23612586 0.80 ACHE (0.75) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL11808972 0.77 ADORA3 (0.41) ALDH1A1MAPTRAB9AGAAKMT2A
SCHEMBL27761307 0.77 NQO2 (0.48) ALDH1A1MAPTRAB9AGAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 539 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118320093-A Application of anticancer, antiallergic and antibacterial drugs in preparation of colorectal cancer drugs for treating clostridium nucleatum infection 兰州大学 2024-07-12 CN claimed
CN-115531388-B Pharmaceutical composition for treating tuberculosis 首都医科大学附属北京胸科医院 2024-03-22 CN claimed
CN-117652038-A Electrode assembly, secondary battery, battery module, battery pack, and power consumption device 宁德时代新能源科技股份有限公司 2024-03-05 CN claimed
CN-117343021-A Preparation method of chlorophenophenazine 山西立业制药有限公司 2024-01-05 CN claimed
CN-117043600-A Mycobacterium tuberculosis compositions and methods 石万良 2023-11-10 CN claimed
CN-116982170-A Negative electrode plate, secondary battery, battery module, battery pack and power utilization device 宁德时代新能源科技股份有限公司 2023-10-31 CN claimed
CN-116406669-A Weeding combination UPL有限公司 2023-07-11 CN claimed
CN-114814013-B Method for rapidly screening unknown chemical hazard residues in aquatic products based on high-resolution mass spectrum database 中国海洋大学 2023-06-02 CN claimed
CN-116194597-A Methods and compositions for drug resistance screening 夸德拉姆生物科学研究所 2023-05-30 CN claimed
CN-116075296-A Transdermal pharmaceutical preparation for treating multiple sclerosis 长矛治疗股份有限公司 2023-05-05 CN claimed
CN-111093707-A Tubulysin homolog conjugates containing branched linkers 杭州多禧生物科技有限公司 2020-05-01 CN claimed
WO-2020011127-A1 MUTANT PSII D1 OR PSBA D1 PROTEIN, CODING NUCLEIC ACID THEREOF AND USE THEREOF 青岛清原化合物有限公司 2020-01-16 WO claimed
EP-1317304-B1 SLOW RELEASE PHARMACEUTICAL PREPARATION AND METHOD OF ADMINISTERING SAME PALMAYA PTY LTD (AU) 2011-04-27 EP claimed
US-6309669-B1 Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2001-10-30 US claimed
EP-0758229-A1 TOPICAL POLYMERIC DRUG DELIVERY SYSTEM MERCK FROSST CANADA INC. (CA) 1997-02-19 EP claimed
WO-1995030409-A1 TOPICAL POLYMERIC DRUG DELIVERY SYSTEM MERCK FROSST CANADA INC. (CA) 1995-11-16 WO claimed
EP-0396943-B1 Optical storage medium and storage process NIPPON TELEGRAPH & TELEPHONE (JP) 1995-07-05 EP claimed
US-5124944-A OPTICAL STORAGE MEDIUM AND STORAGE PROCESS NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-23 US claimed
EP-0396943-A2 Optical storage medium and storage process NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-11-14 EP claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed