SCHEMBL2652708

SCHEMBL2652708

CC(C)(C)OC(=O)c1ccccn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
L3MBTL1 Q9Y468 4/20 0.52
LMNA P02545 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
P4HTM Q9NXG6 1/20 0.52
KDM4E B2RXH2 2/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.49
HPGDS O60760 1/20 0.48
APP P05067 1/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29550139 1.00 ALDH1A1 (0.55) ALDH1A1CES2CES1L3MBTL1LMNA
Fluoride SCHEMBL28087422 0.98 ALDH1A1 (0.53) ALDH1A1CES2CES1L3MBTL1LMNA
Trifluoroacetic Acid SCHEMBL27586292 0.91 L3MBTL1 (0.47) ALDH1A1CES2CES1L3MBTL1LMNA
SCHEMBL28275196 0.86 ALDH1A1 (0.52) ALDH1A1CES2CES1L3MBTL1LMNA
SCHEMBL29053183 0.83 MAPT (0.72) ALDH1A1L3MBTL1KDM4EPOLBMAPT
SCHEMBL28655311 0.82 ALDH1A1 (0.53) ALDH1A1L3MBTL1KDM4EMAPTAPP
SCHEMBL29224810 0.82 L3MBTL1 (0.46) ALDH1A1CES2CES1L3MBTL1LMNA
SCHEMBL3659035 0.81 CES2 (0.53) ALDH1A1CES2CES1L3MBTL1LMNA
SCHEMBL28655313 0.81 NPC1 (0.45) ALDH1A1CES2CES1L3MBTL1LMNA
SCHEMBL11532434 0.79 L3MBTL1 (0.53) ALDH1A1CES2CES1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998281-A Neurotrophic receptor tyrosine kinase (NTRK) inhibitors and methods of use thereof 贝勒医学院 2025-05-13 CN claimed
CN-109415371-A Novel 2-acylamino thiazole derivative and preparation method and application thereof 四川科伦博泰生物医药股份有限公司 2019-03-01 CN claimed
CN-107108478-A URAT1 inhibitors 日本化学药品株式会社 2017-08-29 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
CN-121586713-A Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases 百济神州(苏州)生物科技有限公司 2026-02-27 CN disclosed
CN-120129485-A Methods, compositions, and systems for assessing visual function 英属开曼群岛商倍亮生物有限公司 2025-06-10 CN disclosed
CN-112239468-B Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof 印多尔印度理工学院 2025-05-27 CN disclosed
CN-119998281-A Neurotrophic receptor tyrosine kinase (NTRK) inhibitors and methods of use thereof 贝勒医学院 2025-05-13 CN disclosed
CN-116410207-B Ubiquitin specific protease inhibitor and preparation method and application thereof 杭州普济远成生物医药科技有限公司 2025-05-06 CN disclosed
CN-114450284-B 6, 7-Dihydro-5H-pyrido [2,3-C ] pyridazine derivatives as BCL-XL protein inhibitors 法国施维雅药厂 2024-05-07 CN disclosed
CN-1353695-A Heterocyclically substituted benzimidazoles, production and application thereof BASF AG (DE) 2002-06-12 CN disclosed
CN-1332743-A Cell adhesion-inhibiting antinflammatory compounds ABBOTT CO (US) 2002-01-23 CN disclosed
CN-1246849-A 2-methoxyimino-2- (pyridyloxymethyl) phenylacetamide fungicides having carboxylic acid substituents on the pyridine ring DOW AGROSCIENCES CORP (US) 2000-03-08 CN disclosed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US disclosed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO disclosed
CN-1200374-A Vitronectin receptor antagonists, their preparation and use HOECHST AG (DE) 1998-12-02 CN disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed