Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652708 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL29550139 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| Fluoride SCHEMBL28087422 | 0.84 | ALDH1A1 (0.53) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL3659035 | 0.79 | CES2 (0.53) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| Trifluoroacetic Acid SCHEMBL27586292 | 0.78 | L3MBTL1 (0.47) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL11532434 | 0.76 | L3MBTL1 (0.53) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL29576494 | 0.76 | KDM4E (0.68) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL30166417 | 0.76 | KDM4E (0.68) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL247011 | 0.76 | KDM4E (0.68) | ALDH1A1CES2CES1L3MBTL1LMNA | |
| SCHEMBL31431897 | 0.75 | PKM (0.45) | ALDH1A1CES2CES1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219603-A | Substituted indazoles for treating and preventing allergic and/or inflammatory diseases in animals | 拜耳动物保健有限责任公司 | 2019-01-15 | — | — | CN | disclosed |