Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26523738 | 0.83 | — | — | |
| SCHEMBL26527389 | 0.79 | EPHX2 (0.32) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL18937380 | 0.78 | ESR1 (0.33) | — | |
| SCHEMBL10271203 | 0.74 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL26526004 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL26526008 | 0.74 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL5791247 | 0.73 | LMNA (0.33) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL24939223 | 0.72 | CHRNA1 (0.36) | CHRNA1CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL24087864 | 0.71 | POLB (0.40) | CHRNB4CHRNA3 | |
| SCHEMBL21184985 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | EDGEWISE THERAPEUTICS, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321091-A1 | SUBSTITUTED PYRIDAZINONES FOR USE IN THE TREATMENT OF NEUROMUSCULAR DISEASES | IL6, MUSK, SMN1; SMN2 | CHRNA1 51/4885CHRNB4 162/4885CHRNA3 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.