SCHEMBL26527736

SCHEMBL26527736

CCc1nc2nc(C)c(OC)cn2c1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
F11 P03951 1/20 0.36
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
DPP4 P27487 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
GPR35 Q9HC97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24689506 0.87 GABRP (0.34) KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2
SCHEMBL26527689 0.87 ALDH1A1 (0.45) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL23099608 0.82 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10
SCHEMBL23099510 0.81 DPP4 (0.32) KDM4EALDH1A1HPGDHSD17B10DPP4
SCHEMBL26527717 0.76 ALKBH1 (0.36) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL26527683 0.75 KDM4E (0.49) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL23099405 0.74 EGLN1 (0.38) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL23099556 0.73 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10GLA
SCHEMBL26527709 0.73 GABRP (0.37) KDM4EALDH1A1HPGDHSD17B10MAPK1
SCHEMBL23099412 0.71 POLB (0.33) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023073090-A1 IMIDAZOPYRIDINE AMIDES AND RELATED COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS Janssen Sciences Ireland Unlimited Company (IE) 2023-05-04 WO disclosed