Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23099413 | 0.86 | KDM4E (0.43) | L3MBTL1LMNA | |
| SCHEMBL26527717 | 0.82 | ALKBH1 (0.36) | LMNAALKBH1 | |
| SCHEMBL23099556 | 0.80 | KDM4E (0.33) | TP53 | |
| SCHEMBL23099456 | 0.79 | AGBL2 (0.34) | — | |
| SCHEMBL23099492 | 0.79 | GABRP (0.32) | — | |
| SCHEMBL23099631 | 0.78 | CYP2C9 (0.39) | POLBTDP1L3MBTL1LMNATP53 | |
| SCHEMBL23099441 | 0.78 | ALKBH1 (0.38) | POLBLMNAALKBH1 | |
| SCHEMBL24689674 | 0.74 | CYP2C9 (0.35) | TDP1L3MBTL1 | |
| SCHEMBL24689506 | 0.74 | GABRP (0.34) | LMNATP53 | |
| SCHEMBL26527736 | 0.71 | KDM4E (0.40) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021048342-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-03-18 | — | — | WO | disclosed |