Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24642859 | 0.92 | TDP1 (0.36) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL26528591 | 0.86 | CA1 (0.42) | TDP1NPSR1KMT2APOLBGAA | |
| SCHEMBL26527755 | 0.84 | GLP1R (0.39) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL31538101 | 0.84 | GLP1R (0.39) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL30604905 | 0.83 | GLP1R (0.39) | TDP1ATMNPSR1POLBMAPT | |
| SCHEMBL24642860 | 0.81 | CA2 (0.36) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL24642846 | 0.78 | CAPN1 (0.39) | TDP1ATMMEN1KMT2AITGB1 | |
| SCHEMBL21602732 | 0.77 | MEN1 (0.50) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL24642734 | 0.77 | NPSR1 (0.42) | TDP1ATMNPSR1MEN1KMT2A | |
| SCHEMBL31601080 | 0.76 | MEN1 (0.57) | TDP1MEN1KMT2AGAAFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |