SCHEMBL30604905

SCHEMBL30604905

CSc1ncc(C#CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)N[C@H](C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)O)C(C)C)cn1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 9/20 0.39
▸ SUCNR1 Q9BXA5 3/20 0.33
▸ PSEN1 P49768 3/20 0.33
▸ PSEN2 P49810 3/20 0.33
▸ APH1B Q8WW43 3/20 0.33
▸ NCSTN Q92542 3/20 0.33
▸ APH1A Q96BI3 3/20 0.33
▸ PSENEN Q9NZ42 3/20 0.33
▸ SCTR P47872 1/20 0.33
▸ TDP1 Q9NUW8 3/20 0.32
▸ ATM Q13315 2/20 0.32
▸ MAPT P10636 1/20 0.32
▸ IL23R Q5VWK5 1/20 0.32
▸ ADRB2 P07550 1/20 0.32
▸ HTR1A P08908 1/20 0.32
▸ POLB P06746 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31538101 0.98 GLP1R (0.39) GLP1RSUCNR1PSEN1PSEN2APH1B
SCHEMBL26527755 0.98 GLP1R (0.39) GLP1RSUCNR1PSEN1PSEN2APH1B
SCHEMBL24642859 0.91 TDP1 (0.36) SUCNR1TDP1ATMMAPTPOLB
SCHEMBL26527638 0.84 NPSR1 (0.38) GLP1RSUCNR1TDP1ATMMAPT
SCHEMBL31538096 0.84 NPSR1 (0.38) GLP1RSUCNR1TDP1ATMMAPT
SCHEMBL26528590 0.83 TDP1 (0.40) SUCNR1TDP1ATMMAPTPOLB
SCHEMBL30604904 0.81 FOLH1 (0.41) GLP1RSUCNR1
SCHEMBL24642860 0.81 CA2 (0.36) SUCNR1TDP1ATMMAPTPOLB
SCHEMBL24642847 0.80 KMT2A (0.34) GLP1RSUCNR1TDP1ATMMAPT
SCHEMBL26527959 0.80 FOLH1 (0.40) GLP1RSUCNR1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748843-A2 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2026-05-27 — — EP disclosed
EP-4556026-A1 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2025-05-21 — — EP disclosed
EP-4552654-A1 ANTIBODY-DRUG CONJUGATE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2025-05-14 — — EP disclosed
US-20250144229-A1 CONJUGATE OF ANTIBODY-ERIBULIN OR DERIVATIVE THEREOF, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF MEDILINK THERAPEUTICS (SUZHOU) CO., LTD. (CN) 2025-05-08 — — US disclosed
EP-4480499-A1 CONJUGATE OF ANTIBODY-ERIBULIN OR DERIVATIVE THEREOF, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2024-12-25 — — EP disclosed
US-20240108745-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF MEDILINK THERAPEUTICS (SUZHOU) CO., LTD. (CN) 2024-04-04 — — US disclosed
EP-4257154-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Medilink Therapeutics (Suzhou) Co., Ltd. (CN) 2023-10-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250144229-A1 CONJUGATE OF ANTIBODY-ERIBULIN OR DERIVATIVE THEREOF, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF ERLIN1, WEE1, ERLIN2 GLP1R 1309/4885SUCNR1 1120/4885PSEN1 2069/4885
US-20240108745-A1 BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF CTSL, VIP, FURIN GLP1R 110/4885SUCNR1 676/4885PSEN1 2886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback