SCHEMBL26528843

SCHEMBL26528843

Cc1cc(-c2ccc3c(c2)c2cc(-c4cc(C)cc(C(F)(F)F)c4)ccc2n3-c2ccccc2-c2ccc(-c3cccc4ccccc34)cc2)cc(C(F)(F)F)c1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ENPP1 P22413 3/20 0.34
ENPP3 O14638 1/20 0.34
ICMT O60725 5/20 0.33
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA9 Q16790 4/20 0.33
PPARG P37231 2/20 0.33
PPARA Q07869 2/20 0.33
FLT3 P36888 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
PPARD Q03181 1/20 0.32
MAT2A P31153 1/20 0.31
POLB P06746 1/20 0.31
MCL1 Q07820 1/20 0.31
BAD Q92934 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26528845 0.94 CA12 (0.35) ENPP1ICMTCA12CA1CA2
SCHEMBL26532394 0.92 ICMT (0.38) ICMTCA12CA1CA2CA9
SCHEMBL26529015 0.90 ICMT (0.36) ICMT
SCHEMBL26528844 0.90 CYP1A2 (0.35) ENPP1ICMTMAT2AMCL1BAD
SCHEMBL26533678 0.90 ICMT (0.34) ENPP1ICMTCA12CA1CA2
SCHEMBL26529003 0.89 ICMT (0.36) ICMT
SCHEMBL26528984 0.89 ICMT (0.37) ICMT
SCHEMBL26528959 0.89 ICMT (0.34) ENPP1ICMTCYP2C9CYP2C19
SCHEMBL26528887 0.88 KIF11 (0.37) ENPP1ICMT
SCHEMBL26529348 0.87 ICMT (0.36) ICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ENPP1 1414/4885ENPP3 1502/4885ICMT 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.