SCHEMBL26529558

SCHEMBL26529558

Fc1cc(F)cc(-c2cc(-c3cc(F)cc(F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(F)cc(F)c6)cc(-c6cc(F)cc(F)c6)c5)ccc3n4-c3ccccc3F)c2)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.36
NTRK1 P04629 1/20 0.33
NTRK3 Q16288 1/20 0.33
NTRK2 Q16620 1/20 0.33
PGR P06401 1/20 0.33
MPI P34949 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MGLL Q99685 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529581 0.90 MAP4K4 (0.33) MAP4K4NTRK1NTRK3NTRK2PGR
SCHEMBL26529605 0.89 MAP4K4 (0.35) MAP4K4PGR
SCHEMBL26529551 0.89 NR3C1 (0.36) GAANOTUM
SCHEMBL26529607 0.88 MAP4K4 (0.34) MAP4K4NTRK1NTRK3NTRK2PGR
SCHEMBL26529065 0.86 TSHR (0.36) MAP4K4PGRMPIALDH1A1SMN1; SMN2
SCHEMBL26529553 0.86 MAP4K4 (0.38) MAP4K4PGRALDH1A1
SCHEMBL26529010 0.86 MAP4K4 (0.35) MAP4K4NTRK1NTRK3NTRK2PGR
SCHEMBL26528744 0.84 TSHR (0.36) MAP4K4NTRK1NTRK3NTRK2PGR
SCHEMBL26529107 0.84 MAPT (0.37) MAP4K4PGRALDH1A1MEN1KMT2A
SCHEMBL26528758 0.83 HTR7 (0.36) MAP4K4NTRK1NTRK3NTRK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 MAP4K4 4467/4885NTRK1 1835/4885NTRK3 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.