SCHEMBL26529581

SCHEMBL26529581

Fc1cc(F)cc(-c2cc(-c3cc(F)cc(F)c3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6cc(F)cc(F)c6)cc(-c6cc(F)cc(F)c6)c5)ccc3n4-c3ccccc3-c3ccccc3F)c2)c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 2/20 0.33
PTPRC P08575 1/20 0.32
PTPN1 P18031 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.31
ICMT O60725 1/20 0.31
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
NTRK1 P04629 1/20 0.30
NTRK3 Q16288 1/20 0.30
NTRK2 Q16620 1/20 0.30
TDO2 P48775 1/20 0.30
IDO2 Q6ZQW0 1/20 0.30
SSTR2 P30874 1/20 0.30
PIM1 P11309 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529605 0.93 MAP4K4 (0.35) MAP4K4PTPRCPTPN1CYP11B1CYP11B2
SCHEMBL26529579 0.92 MAP4K4 (0.37) MAP4K4PTPRCPTPN1CYP11B1CYP11B2
SCHEMBL26529607 0.90 MAP4K4 (0.34) MAP4K4HTR7NTRK1NTRK3NTRK2
SCHEMBL26529558 0.90 MAP4K4 (0.36) MAP4K4NTRK1NTRK3NTRK2PGR
SCHEMBL26529010 0.88 MAP4K4 (0.35) MAP4K4ICMTHTR7NTRK1NTRK3
SCHEMBL26528762 0.86 SSTR2 (0.34) MAP4K4ICMTHTR7NTRK1NTRK3
SCHEMBL26528758 0.86 HTR7 (0.36) MAP4K4ICMTHTR1AHTR7NTRK1
SCHEMBL26529553 0.85 MAP4K4 (0.38) MAP4K4PTPRCPTPN1CYP11B1CYP11B2
SCHEMBL26528794 0.85 FEN1 (0.34) MAP4K4HTR7NTRK1NTRK3NTRK2
SCHEMBL26528772 0.84 HTR7 (0.35) MAP4K4ICMTHTR1AHTR7NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 MAP4K4 4467/4885PTPRC 924/4885PTPN1 2106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.