Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26529974 | 0.79 | ABCB1 (0.52) | SMN1; SMN2ABCB1ABCC1ABCG2MAPT | |
| SCHEMBL23260550 | 0.77 | CHRM2 (0.47) | SMN1; SMN2ABCB1ABCC1ABCG2MAPT | |
| SCHEMBL8436051 | 0.77 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTCCR3ALDH1A1LMNA | |
| SCHEMBL38663614 | 0.77 | ALDH1A1 (0.52) | SMN1; SMN2ABCB1ABCC1ABCG2ALDH1A1 | |
| SCHEMBL8252239 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTCCR3ALDH1A1LMNA | |
| SCHEMBL38663566 | 0.75 | ABCB1 (0.51) | ABCB1ABCC1ABCG2MAPTALDH1A1 | |
| SCHEMBL26529969 | 0.75 | CHRM2 (0.52) | SMN1; SMN2ALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL14393396 | 0.73 | SMN1; SMN2 (0.69) | SMN1; SMN2MAPTCCR3ALDH1A1LMNA | |
| SCHEMBL19059240 | 0.71 | GPR119 (0.58) | — | |
| SCHEMBL5359069 | 0.70 | CCR3 (0.62) | SMN1; SMN2CCR3ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | SMN1; SMN2 3408/4885ABCB1 3325/4885ABCC1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.