Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20753263 | 0.74 | MAPT (0.42) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL10066790 | 0.72 | TOP2A (0.44) | TSHRMAPTSMN1; SMN2LMNA | |
| SCHEMBL10066795 | 0.72 | CYP2C9 (0.32) | CYP2C9TSHR | |
| SCHEMBL576229 | 0.71 | SMN1; SMN2 (0.48) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL5704664 | 0.68 | TRPA1 (0.53) | CYP2C9TSHRHSD17B10MAOATRPA1 | |
| SCHEMBL29201828 | 0.68 | HPGD (0.55) | CYP2C9TSHRMAPTHPGDSMN1; SMN2 | |
| SCHEMBL18271751 | 0.68 | KMT2A (0.41) | CYP2C9HSD17B10MTNR1AMTNR1BLMNA | |
| SCHEMBL10066794 | 0.67 | CYP2C9 (0.37) | CYP2C9TSHR | |
| SCHEMBL6069095 | 0.67 | MTNR1A (0.46) | CYP2C9TSHRSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL6069094 | 0.67 | MTNR1A (0.46) | CYP2C9TSHRSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322742-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322742-A1 | ORTHOESTER COMPOSITIONS FOR AFFINITY PURIFICATION OF OLIGONUCLEOTIDES | RNGTT, OSBPL8, DCLRE1B | CYP2C9 2673/4885TSHR 428/4885MAPT 1562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.