SCHEMBL26532

SCHEMBL26532

c1ccc(CN2CCCCC2)cc1

nearest known ligand 0.77

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.77
HRH3 Q9Y5N1 3/20 0.77
HRH4 Q9H3N8 1/20 0.68
CYP2D6 P10635 1/20 0.67
CYP2C19 P33261 1/20 0.67
ALDH1A1 P00352 4/20 0.65
KDM4E B2RXH2 1/20 0.65
MC4R P32245 1/20 0.63
DRD4 P21917 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.60
TDP1 Q9NUW8 1/20 0.60
SLC6A3 Q01959 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8327 1.00 SIGMAR1 (0.77) SIGMAR1HRH3HRH4CYP2D6CYP2C19
SCHEMBL688047 1.00 SIGMAR1 (0.77) SIGMAR1HRH3HRH4CYP2D6CYP2C19
SCHEMBL11585348 1.00 SIGMAR1 (0.77) SIGMAR1HRH3HRH4CYP2D6CYP2C19
SCHEMBL11141692 1.00 SIGMAR1 (0.77) SIGMAR1HRH3HRH4CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL7409551 0.98 SIGMAR1 (0.74) SIGMAR1HRH3HRH4CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL4774633 0.98 SIGMAR1 (0.74) SIGMAR1HRH3HRH4CYP2D6CYP2C19
Bromide SCHEMBL10730905 0.98 SIGMAR1 (0.74) SIGMAR1HRH3HRH4CYP2D6CYP2C19
SCHEMBL13952 0.98 SIGMAR1 (0.81) SIGMAR1HRH3HRH4CYP2D6CYP2C19
SCHEMBL1777747 0.98 SIGMAR1 (0.81) SIGMAR1HRH3HRH4CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL5923800 0.96 SIGMAR1 (0.71) SIGMAR1HRH3HRH4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4786 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384031-B1 None US claimed
US-6392040-B1 None US claimed
CN-122059995-A Organic-inorganic hybrid antimony halide and preparation method and application thereof 洛阳师范学院 2026-05-19 CN claimed
CN-119019639-B Thermoplastic polyurethane elastomer with low internal heat generation and preparation method and application thereof 万华化学集团股份有限公司 2026-05-19 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-120051457-A Oxalic acid amide compound, pharmaceutical composition containing oxalic acid amide compound, preparation method and application of oxalic acid amide compound 四川科伦博泰生物医药股份有限公司 2025-05-27 CN claimed
CN-119912454-A Antitumor compound and preparation method and application thereof 承德医学院 2025-05-02 CN claimed
WO-2025022031-A1 NEW DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2025-01-30 WO claimed
CN-119060026-A Benzyl piperidine-containing formononetin derivative and preparation method and application thereof 贵州大学 2024-12-03 CN claimed
CN-119019639-A Thermoplastic polyurethane elastomer with low internal heat generation and preparation method and application thereof 万华化学集团股份有限公司 2024-11-26 CN claimed
US-4709010-A TREATING OR PREVENTING HYPERTENSION OR HYPERALDESTERONISM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-11-24 US claimed
EP-0238211-A2 Dihydropyridines, process for their preparation and their use as medicaments GLAXO S.p.A. (IT) 1987-09-23 EP claimed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 EP claimed
EP-0109317-B1 PHENYL-1-PIPERIDINO-2-PROPANOL DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM SYNTHELABO (FR) 1986-12-30 EP claimed
EP-0179352-A2 Peptides MERCK PATENT GmbH (DE) 1986-04-30 EP claimed
EP-0161588-A2 Diamino acid derivatives MERCK PATENT GmbH (DE) 1985-11-21 EP claimed
EP-0157260-A1 4,7-Dihydropyrazolo(3,4-b)Pyridine derivatives SHIONOGI & CO., LTD. (JP) 1985-10-09 EP claimed
EP-0109317-A2 Phenyl-1-piperidino-2-propanol derivatives, their preparation and medicaments containing them SYNTHELABO (FR) 1984-05-23 EP claimed
EP-0106275-A2 1,4-Dihydropyridine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-04-25 EP claimed
US-4016263-A BACTERICIDES BOEHRINGER INGELHEIM GMBH (DT) 1977-04-05 US claimed