Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.81 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.73 |
| ▸ | MC4R | P32245 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1777747 | 1.00 | SIGMAR1 (0.81) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| SCHEMBL26532 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| Bromide SCHEMBL10447698 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| Ammonia Solution, Strong SCHEMBL3699405 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| SCHEMBL8327 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| SCHEMBL688047 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| SCHEMBL11585348 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| SCHEMBL11141692 | 0.98 | SIGMAR1 (0.77) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| Hydrochloric Acid SCHEMBL7409551 | 0.95 | SIGMAR1 (0.74) | SIGMAR1HRH3MC4RHRH4DRD4 | |
| Bromide SCHEMBL10730905 | 0.95 | SIGMAR1 (0.74) | SIGMAR1HRH3MC4RHRH4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3248 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948021-A | Nitrogen-containing heterocyclic derivative, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119285519-B | Preparation method of 5,5' -dimethylpyrrolidine-3-alcohol | 无锡科华生物科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119591581-A | Amide heterocyclic derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-119285519-A | Preparation method of 5,5' -dimethylpyrrolidine-3-alcohol | 无锡科华生物科技有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-118812512-A | Thioamide derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-116396243-B | Method for poly-fluoroaryl of aromatic hydrocarbon | 贵州民族大学 | 2024-10-18 | — | — | CN | claimed |
| WO-2024109918-A1 | GSPT1 DEGRADATION AGENT AND USE THEREOF IN MEDICINE | 西藏海思科制药有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117903016-A | Fluorosulfonyl sulfonimide salt, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-116284017-B | Method for preparing amide compound by utilizing enzyme-like efficient catalytic oxidation | 中国科学院青岛生物能源与过程研究所 | 2024-03-22 | — | — | CN | claimed |
| EP-0543919-B1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS IN THE MANUFACTURE OF A MEDICAMENT FOR TREATMENT OF CNS DISEASES | SEARLE & CO (US) | 1996-04-10 | — | — | EP | claimed |
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | claimed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | claimed |
| EP-0543919-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES. | SEARLE & CO (US) | 1993-06-02 | — | — | EP | claimed |
| WO-1992003131-A1 | USE OF HETEROCYCLIC AMINO-ALCOHOL COMPOUNDS FOR TREATMENT OF CNS DISEASES | G.D. SEARLE & CO. (US) | 1992-03-05 | — | — | WO | claimed |
| US-5051432-A | Heterocyclic 1,4 dihydropyridine derivatives | GLAXO, S.P.A. (IT) | 1991-09-24 | — | — | US | claimed |
| EP-0157260-B1 | 4,7-DIHYDROPYRAZOLO(3,4-B)PYRIDINE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1990-06-13 | — | — | EP | claimed |
| US-4873334-A | HYPOTENSIVE AGENTS, CORONARY VASODILATORS | SHIONOGI & CO., LTD. (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0157260-A1 | 4,7-Dihydropyrazolo(3,4-b)Pyridine derivatives | SHIONOGI & CO., LTD. (JP) | 1985-10-09 | — | — | EP | claimed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | claimed |