Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.77 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | DRD4 | P21917 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26532 | 1.00 | SIGMAR1 (0.77) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| SCHEMBL688047 | 1.00 | SIGMAR1 (0.77) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| SCHEMBL11585348 | 1.00 | SIGMAR1 (0.77) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| SCHEMBL11141692 | 1.00 | SIGMAR1 (0.77) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7409551 | 0.98 | SIGMAR1 (0.74) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL4774633 | 0.98 | SIGMAR1 (0.74) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| Bromide SCHEMBL10730905 | 0.98 | SIGMAR1 (0.74) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| SCHEMBL13952 | 0.98 | SIGMAR1 (0.81) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| SCHEMBL1777747 | 0.98 | SIGMAR1 (0.81) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL5923800 | 0.96 | SIGMAR1 (0.71) | SIGMAR1HRH3HRH4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55162746-A | — | — | None | — | — | JP | disclosed |
| CN-118695874-A | Cancer therapy with TLR7/8 agonists | 阿森迪斯药物肿瘤股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-114944459-B | Organic electroluminescent device | 长春海谱润斯科技股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| WO-2024124279-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CERTA THERAPEUTICS PTY LTD (AU) | 2024-06-20 | — | — | WO | disclosed |
| WO-2024124287-A1 | COMPOUNDS FOR TREATING VIRAL INFECTION | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2024-06-20 | — | — | WO | disclosed |
| US-20240173696-A1 | FUNCTIONALISED HYDROGELS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-05-30 | — | — | US | disclosed |
| US-20240166643-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2024-05-23 | — | — | US | disclosed |
| US-20240132511-A1 | TREATMENTS OF PRADER-WILLI SYNDROME | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2024-04-25 | — | — | US | disclosed |
| CN-117903188-A | Heterocyclic compound and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| WO-2024073794-A1 | SUBJECT SELECTION FOR 11β-HSD1 INHIBITOR TREATMENT | Actinogen Medical Limited (AU) | 2024-04-11 | — | — | WO | disclosed |
| EP-0924227-B1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR CORP (JP) | 2004-03-10 | — | — | EP | disclosed |
| US-20030125448-A1 | A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-07-03 | — | — | US | disclosed |
| EP-1318172-A1 | Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6353099-B1 | USED FOR PREVENTION OR TREATMENT OF DISEASES, DISORDERS, CONDITIONS OR SYMPTOMS MEDIATED BY CELL ADHESION IN MAMMAL | MERCK & CO., INC. | 2002-03-05 | — | — | US | disclosed |
| WO-2001014328-A2 | SUBSTITUTED UREAS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 2001-03-01 | — | — | WO | disclosed |
| US-6191234-B1 | CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD | JSR CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924227-A1 | Conjugated diolefin-based copolymer rubber and composition thereof | JSR Corporation (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-4396698-A | CROSSLINKED CATIONIC ADDITION COPOLYMERS AND HYDROPHOBIC PHENOLIC-TYPE COMPOUNDS; LIGHT SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| US-4390712-A | Aqueous solution of cationic organosilicon compounds and process for the production of the solutions | DEGUSSA AG (DE) | 1983-06-28 | — | — | US | disclosed |
| JP-S55162746-A | PREPARATION OF AMINE DERIVATIVE | GRELAN PHARMACEUT CO LTD | 1980-12-18 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132511-A1 | TREATMENTS OF PRADER-WILLI SYNDROME | COMT, HSD17B3, HSD3B1 | SIGMAR1 2787/4885HRH3 2352/4885HRH4 1982/4885 |
| US-20240166643-A1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | ABL1, TPMT, IDH2 | SIGMAR1 648/4885HRH3 586/4885HRH4 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.