Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 9/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 5/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830855 | 0.95 | THRB (0.50) | THRBESR1ESR2MCL1THRA | |
| SCHEMBL25830902 | 0.95 | THRB (0.50) | THRBESR1ESR2MCL1HPGD | |
| SCHEMBL12255590 | 0.92 | THRB (0.41) | THRBHPGDTSHRKMT2ANPC1 | |
| SCHEMBL12149338 | 0.89 | THRB (0.40) | THRBNAAAHPGDTSHRKMT2A | |
| SCHEMBL13783953 | 0.89 | THRB (0.68) | THRBTHRANAAAHPGDTSHR | |
| SCHEMBL22920936 | 0.88 | THRB (0.39) | THRBHPGDTSHRNPC1ALDH1A1 | |
| SCHEMBL13937443 | 0.88 | THRB (0.39) | THRBHPGDTSHRNPC1ALDH1A1 | |
| SCHEMBL10092988 | 0.87 | THRB (0.44) | THRBHPGDTSHRKMT2ANPC1 | |
| SCHEMBL12534114 | 0.86 | HCAR2 (0.45) | THRBNAAAHPGDKMT2ANPC1 | |
| SCHEMBL16625916 | 0.86 | HCAR2 (0.45) | THRBNAAAHPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230324818-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCING METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-20230324818-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCING METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2023-10-12 | — | — | US | disclosed |