SCHEMBL26533147

SCHEMBL26533147

CC(C)(C)c1ccc(-c2ccccc2-n2c3ccc(-c4cc(C#N)cc(C#N)c4)cc3c3cc(-c4cc(C#N)cc(C#N)c4)ccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
AKT1 P31749 1/20 0.34
SGK1 O00141 1/20 0.34
S1PR1 P21453 1/20 0.34
PTPN5 P54829 1/20 0.33
PGR P06401 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
PDK2 Q15119 2/20 0.31
KDM1A O60341 1/20 0.31
PTAFR P25105 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
PTGER4 P35408 1/20 0.31
SERPINE1 P05121 1/20 0.30
GRM2 Q14416 1/20 0.30
CCR9 P51686 1/20 0.30
CSNK1D P48730 1/20 0.30
CSNK1G2 P78368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26539720 0.91 KIF11 (0.35) KIF11PGRPDK2
SCHEMBL26529548 0.91 KIF11 (0.35) KIF11PGRPDK2
SCHEMBL26533180 0.89 PDK2 (0.35) PGRPDK2PTGER4
SCHEMBL26532995 0.89 PGR (0.37) AKT1PGRPDK2
SCHEMBL26537689 0.88 PGR (0.37) AKT1PGRPDK2
SCHEMBL26529547 0.87 TRPA1 (0.32) KIF11PGR
SCHEMBL28371604 0.87 KIF11 (0.40) KIF11AKT1SGK1PTPN5PGR
SCHEMBL28367117 0.86 KIF11 (0.49) KIF11S1PR1PGRFNTAFNTB
SCHEMBL23127518 0.86 KIF11 (0.38) KIF11SGK1PTPN5PGRFNTA
SCHEMBL26539522 0.86 KIF11 (0.32) KIF11PGRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 KIF11 3651/4885AKT1 4255/4885SGK1 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.