SCHEMBL26533882

SCHEMBL26533882

N#Cc1cc(F)cc(-c2ccc3c(c2)c2cc(-c4cc(F)cc(C#N)c4)ccc2n3-c2ccccc2-c2ccccc2-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PGR P06401 17/20 0.47
MAP4K4 O95819 1/20 0.41
AR P10275 2/20 0.37
METAP2 P50579 1/20 0.35
NR3C1 P04150 1/20 0.35
NR3C2 P08235 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532980 0.92 PGR (0.36) PGRMAP4K4METAP2
SCHEMBL26528802 0.91 PGR (0.39) PGRMAP4K4AR
SCHEMBL26528762 0.88 SSTR2 (0.34) PGRMAP4K4METAP2NR3C1
SCHEMBL26533225 0.87 PGR (0.34) PGRMAP4K4METAP2
SCHEMBL26532995 0.87 PGR (0.37) PGRMAP4K4METAP2
SCHEMBL26533055 0.86 MEN1 (0.35) PGRMAP4K4METAP2
SCHEMBL26528798 0.86 PGR (0.40) PGRMAP4K4
SCHEMBL26537689 0.86 PGR (0.37) PGRMAP4K4METAP2
SCHEMBL28371883 0.85 MEN1 (0.36) PGRMETAP2
SCHEMBL26528772 0.84 HTR7 (0.35) PGRMAP4K4METAP2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 PGR 3828/4885MAP4K4 4467/4885AR 3385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.