SCHEMBL26528798

SCHEMBL26528798

N#Cc1ccc(-c2ccccc2-n2c3ccc(-c4cc(F)cc(F)c4)cc3c3cc(-c4cc(F)cc(F)c4)ccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGR P06401 9/20 0.40
SSTR2 P30874 3/20 0.39
MAP4K4 O95819 1/20 0.37
PDK2 Q15119 1/20 0.36
PTGS1 P23219 1/20 0.35
HTR7 P34969 1/20 0.35
KDM1A O60341 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26528802 0.95 PGR (0.39) PGRSSTR2MAP4K4PDK2PTGS1
SCHEMBL26533180 0.88 PDK2 (0.35) PGRMAP4K4PDK2
SCHEMBL28371534 0.87 GABRA1 (0.40) MAP4K4PDK2HTR7KIF11
SCHEMBL26528758 0.87 HTR7 (0.36) PGRSSTR2MAP4K4HTR7
SCHEMBL26529010 0.87 MAP4K4 (0.35) PGRSSTR2MAP4K4HTR7
SCHEMBL24369964 0.86 PTGER4 (0.35) PGRSSTR2KDM1A
SCHEMBL26533882 0.86 PGR (0.47) PGRMAP4K4
SCHEMBL26528772 0.85 HTR7 (0.35) PGRSSTR2MAP4K4HTR7
SCHEMBL26529607 0.85 MAP4K4 (0.34) PGRSSTR2MAP4K4HTR7
SCHEMBL26533225 0.84 PGR (0.34) PGRMAP4K4PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 PGR 3828/4885SSTR2 4874/4885MAP4K4 4467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.