Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YWHAG | P61981 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26534252 | 0.87 | YWHAG (0.46) | YWHAGCYP4F2CYP4A11ALDH1A1LMNA | |
| SCHEMBL2946934 | 0.76 | CYP4F2 (0.47) | YWHAGCYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL29277507 | 0.76 | YWHAG (0.47) | YWHAGCYP4F2CYP4A11ALDH1A1MEN1 | |
| SCHEMBL533588 | 0.74 | ALDH1A1 (0.58) | CYP4F2CYP4A11ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL26119060 | 0.74 | CTBP2 (0.46) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL9883941 | 0.74 | CYP4F2 (0.44) | YWHAGCYP4F2CYP4A11ALDH1A1MEN1 | |
| Water SCHEMBL28002265 | 0.73 | ALDH1A1 (0.56) | CYP4F2CYP4A11ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13599717 | 0.72 | TSHR (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2SLCO1B3 | |
| SCHEMBL8937633 | 0.71 | CYP4F2 (0.39) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL3193883 | 0.71 | AKR1B1 (0.49) | YWHAGCYP4F2CYP4A11ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257683-A1 | NOVEL URETHANASES FOR THE ENZYMATIC DECOMPOSITION OF POLYURETHANES | Covestro Deutschland AG (DE) | 2023-10-11 | — | — | EP | disclosed |