Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | YWHAG | P61981 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803510 | 0.89 | CYP4F2 (0.46) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL14632173 | 0.87 | PKM (0.50) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL13492095 | 0.84 | MEN1 (0.49) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL20289308 | 0.84 | CYP4F2 (0.64) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2LMNA | |
| SCHEMBL1008790 | 0.81 | YWHAG (0.53) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL13492094 | 0.81 | CYP4Z1 (0.47) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL9883941 | 0.81 | CYP4F2 (0.44) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL6207253 | 0.80 | CYP4Z1 (0.55) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL26534252 | 0.80 | YWHAG (0.46) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM | |
| SCHEMBL12900615 | 0.80 | CYP4Z1 (0.46) | CYP4F2CYP4A11CYP4Z1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1842923-B1 | Methanesulfonylaminoindole derivatives and labeled oligonucleotide probes containing them | ROCHE DIAGNOSTICS GMBH (DE) | 2015-07-15 | — | — | EP | disclosed |
| US-7759470-B2 | Labeling reagent | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| EP-1842923-A1 | Methanesulfonylaminoindole derivatives and labeled oligonucleotide probes containing them. | Roche Diagnostics GmbH (DE) | 2007-10-10 | — | — | EP | disclosed |
| US-20070196852-A1 | Labeling reagent | ROCHE DIAGNOSTICS GMBH (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20040235022-A1 | Quality control method for manufacturing biopolymer arrays | ROCHE DIAGNOSTICS GMBH (DE) | 2004-11-25 | — | — | US | disclosed |
| EP-1466663-A1 | Quality control method for manufacturing nucleic acid arrays | F. HOFFMANN-LA ROCHE AG (CH) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196852-A1 | Labeling reagent | INMT, RNGTT, DUT | CYP4F2 1628/4885CYP4A11 2468/4885CYP4Z1 635/4885 |
| US-20040235022-A1 | Quality control method for manufacturing biopolymer arrays | CTRL, PCBP1, PARG | CYP4F2 2988/4885CYP4A11 3868/4885CYP4Z1 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.