Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959966 | 0.89 | CYP4A11 (0.40) | CYP4F2CYP4A11POLBNPSR1KMT2A | |
| SCHEMBL210161 | 0.87 | PKM (0.42) | CYP4F2CYP4A11POLBKMT2AGAA | |
| SCHEMBL7789892 | 0.85 | POLB (0.42) | POLBKMT2AGAALMNAMEN1 | |
| SCHEMBL9000900 | 0.81 | ALDH1A1 (0.45) | LMNACYP3A4ALDH1A1KDM4ESHBG | |
| SCHEMBL2332010 | 0.81 | SLC22A12 (0.44) | POLBNPSR1KMT2AGAALMNA | |
| SCHEMBL11158364 | 0.79 | CYP4F2 (0.40) | CYP4F2CYP4A11POLBKMT2AGAA | |
| SCHEMBL12900623 | 0.77 | LMNA (0.46) | POLBKMT2AGAALMNAMEN1 | |
| Toluene SCHEMBL1159746 | 0.77 | L3MBTL1 (0.41) | POLBKMT2AGAALMNAMEN1 | |
| Toluene SCHEMBL8994440 | 0.77 | L3MBTL1 (0.41) | POLBKMT2AGAALMNAMEN1 | |
| Toluene SCHEMBL8907280 | 0.77 | L3MBTL1 (0.41) | POLBKMT2AGAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1695712-A | Medicine for relieving cough, reducing sputum and relieving asthma and its preparing process | ZHONGHUI PHARMACY CO LTD CHENG (CN) | 2005-11-16 | — | — | CN | claimed |
| US-RE49517-E1 | Pyrazoles | Janssen Pharmaceuticals, Inc. (US) | 2023-05-02 | — | — | US | disclosed |
| CN-114350257-B | Flexible coating material and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-07-19 | — | — | CN | disclosed |
| CN-114350257-A | Flexible coating material and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2022-04-15 | — | — | CN | disclosed |
| CN-111217822-A | Preparation method of tetrandrine as Chinese medicinal anti-allergy agent | 上海浙星新型材料科技有限公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-3180315-B1 | PYRAZOLES | JANSSEN PHARMACEUTICALS INC (US) | 2020-03-18 | — | — | EP | disclosed |
| US-10155727-B2 | Pyrazoles | Janssen Pharmaceuticals, Inc. (US) | 2018-12-18 | — | — | US | disclosed |
| US-20170275254-A1 | PYRAZOLES | JANSSEN PHARMACEUTICALS INC (US) | 2017-09-28 | — | — | US | disclosed |
| EP-3180315-A1 | PYRAZOLES | Janssen Pharmaceuticals, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016025918-A1 | PYRAZOLES | Janssen Pharmaceuticals, Inc. (US) | 2016-02-18 | — | — | WO | disclosed |
| CN-102764398-A | Medicine for relieving cough, resolving sputum and relieving asthma and preparation method thereof | SICHUAN SUNNYHOPE PHARMACEUTICAL CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-1695712-B | Identification and inspection method of medicine for relieving cough, reducing phlegm and relieving asthma | SICHUAN SHENGHE PHARMACY CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-1695712-A | Medicine for relieving cough, reducing sputum and relieving asthma and its preparing process | ZHONGHUI PHARMACY CO LTD CHENG (CN) | 2005-11-16 | — | — | CN | disclosed |
| EP-0614367-A4 | SUBSTITUTED LACTOSE AND LACTOSAMINE DERIVATIVES AS CELL ADHESION INHIBITORS. | GLYCOMED INC (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1994025478-A1 | 16α,17α-ACETAL GLUCOCORTICOSTEROIDAL DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 1994-11-10 | — | — | WO | disclosed |
| EP-0614367-A1 | SUBSTITUTED LACTOSE AND LACTOSAMINE DERIVATIVES AS CELL ADHESION INHIBITORS | GLYCOMED INCORPORATED (US) | 1994-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275254-A1 | PYRAZOLES | GRIN3A, GRIN1, GRIN2B | CYP4F2 1813/4885CYP4A11 2535/4885POLB 4553/4885 |
| US-10155727-B2 | Pyrazoles | GRIN3A, GRIN1, GRIN2B | CYP4F2 1813/4885CYP4A11 2535/4885POLB 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.