Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.55 |
| ▸ | ESR1 | P03372 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513492 | 0.81 | ESR2 (0.67) | ESR2ESR1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL7520152 | 0.80 | ALDH1A1 (0.57) | ESR2ESR1ALDH1A1LMNANR1I2 | |
| SCHEMBL20034068 | 0.78 | GABRA1 (0.50) | ALDH1A1GABRA1GABRB2TSHRTDP1 | |
| SCHEMBL29494601 | 0.78 | ESR2 (0.74) | ESR2ESR1ALDH1A1ALOX15MAPT | |
| SCHEMBL503213 | 0.78 | ESR2 (0.74) | ESR2ESR1ALDH1A1ALOX15MAPT | |
| SCHEMBL7946603 | 0.77 | ESR1 (0.48) | ESR2ESR1ALDH1A1LMNANR1I2 | |
| SCHEMBL29120292 | 0.77 | ESR2 (0.62) | ESR2ESR1ALDH1A1LMNAMAPT | |
| SCHEMBL29156177 | 0.76 | ALDH1A1 (0.57) | ESR2ESR1ALDH1A1LMNANR1I2 | |
| SCHEMBL28466720 | 0.76 | ALDH1A1 (0.55) | ALDH1A1LMNANR1I2CYP2C9MIF | |
| SCHEMBL7858673 | 0.76 | ALDH1A1 (0.67) | ESR2ESR1ALDH1A1LMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001291-B | Novel triazine compound and synthetic resin composition using same | 株式会社艾迪科 | 2020-06-19 | — | — | CN | disclosed |
| CN-101878264-B | Styrenic polymers as blend components to control adhesion between olefinic substrates | DOW GLOBAL TECHNOLOGIES INC | 2012-11-07 | — | — | CN | disclosed |
| CN-101878264-A | Styrenic polymers as blend components to control adhesion between olefinic substrates | DOW GLOBAL TECHNOLOGIES INC | 2010-11-03 | — | — | CN | disclosed |
| EP-1856090-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006086488-A2 | SUBSTITUTED THIOPHENE DERIVATIVES AS GLUCAGON RECEPTOR ANTAGONISTS, PREPARATION AND THERAPEUTIC USES | ELI LILLY AND COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |