Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411873 | 0.82 | KDM4E (0.47) | GLASMN1; SMN2HSD17B10LMNAGAA | |
| SCHEMBL272351 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2D6CA12CA1CA2 | |
| SCHEMBL19124539 | 0.81 | LIPE (0.58) | SMN1; SMN2CYP2D6CA12CA1CA2 | |
| SCHEMBL3870027 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2D6CA12CA1CA2 | |
| SCHEMBL265501 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2HSD17B10LMNAGAALIPE | |
| Hydrochloric Acid SCHEMBL28256988 | 0.79 | LIPE (0.57) | SMN1; SMN2CYP2D6CA12CA1CA2 | |
| SCHEMBL27725002 | 0.79 | HTT (0.43) | GLASMN1; SMN2CYP2D6CA12CA1 | |
| Hydrochloric Acid SCHEMBL6043366 | 0.79 | SMN1; SMN2 (0.42) | GLASMN1; SMN2CYP2D6CA12CA1 | |
| SCHEMBL9503176 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2CYP2D6HSD17B10LMNACYP2C19 | |
| SCHEMBL9551386 | 0.78 | CA12 (0.47) | SMN1; SMN2CYP2D6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133888-B2 | Hydrazide containing taxane conjugates | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2012-03-13 | — | — | US | disclosed |
| US-20110172226-A1 | NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2011-07-14 | — | — | US | disclosed |
| US-4826815-A | HYPOTENSIVE | ABBOTT LABORATORIES (US) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172226-A1 | NOVEL HYDRAZIDE CONTAINING TAXANE CONJUGATES | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, H1-3, H1-5 | GLA 2307/4885SMN1; SMN2 2189/4885CYP2D6 598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.