Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.44 |
| ▸ | KDM5C | P41229 | 3/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL265501 | 0.98 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2TP53PHF8 | |
| SCHEMBL23375057 | 0.82 | PHF8 (0.43) | KDM4EALDH1A1SMN1; SMN2TP53PHF8 | |
| SCHEMBL265358 | 0.82 | GLA (0.48) | KDM4EALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL16353590 | 0.82 | CA12 (0.50) | KDM4EALDH1A1SMN1; SMN2TP53PHF8 | |
| SCHEMBL3879759 | 0.78 | GNAI3 (0.50) | ALDH1A1SMN1; SMN2TP53HTTLMNA | |
| SCHEMBL271770 | 0.78 | HTT (0.41) | KDM4EALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL2364252 | 0.77 | TP53 (0.50) | KDM4EALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL3878624 | 0.77 | HTT (0.43) | KDM4EALDH1A1TP53HTTLMNA | |
| SCHEMBL493880 | 0.77 | TP53 (0.50) | KDM4EALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL15055257 | 0.76 | HTT (0.43) | KDM4EALDH1A1SMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109310090-B | Pesticidal composition | 先正达参股股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-10674728-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-09 | — | — | US | disclosed |
| US-20190313646-A1 | INSECTICIDE MIXTURES COMPRISING LOLINE ALKALOIDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-17 | — | — | US | disclosed |
| US-20190142010-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-05-16 | — | — | US | disclosed |
| WO-2017215981-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-21 | — | — | WO | disclosed |
| US-9801374-B2 | Active compound combinations comprising carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150189876-A1 | CROP ENHANCEMENT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-09 | — | — | US | disclosed |
| US-20150150253-A1 | CROP ENHANCEMENT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-04 | — | — | US | disclosed |
| EP-2858497-A2 | CROP ENHANCEMENT COMPOSITIONS | Syngenta Participations AG (CH) | 2015-04-15 | — | — | EP | disclosed |
| US-20050020677-A1 | Compounds having prolyl oligopeptidase inhibitory activity, methods for their preparation and their use | ORION CORPORATION (FI) | 2005-01-27 | — | — | US | disclosed |
| EP-1401810-A1 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY, METHODS FOR THEIR PREPARATION AND THEIR USE | ORION CORPORATION (FI) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003004468-A1 | COMPOUNDS HAVING PROLYL OLIGOPEPTIDASE INHIBITORY ACTIVITY, METHODS FOR THEIR PREPARATION AND THEIR USE | ORION CORPORATION (FI) | 2003-01-16 | — | — | WO | disclosed |
| US-4333759-A | Herbicidal 5-cyano-2,3-dihydro-benzofuran-2-ones | FISONS LIMITED (GB) | 1982-06-08 | — | — | US | disclosed |
| US-4263037-A | 5-Cyano-2,3-dihydrobenzofurans useful as herbicides | FISONS LIMITED (GB) | 1981-04-21 | — | — | US | disclosed |
| US-4222767-A | Certain herbicidal sulfonates and sulfamates | FISONS LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| EP-0007719-A2 | Cyanbenzofuran derivatives, processes for their preparation and their use in herbicidal compositions; cyanobenzene, benzodioxepine, benzodioxaphosphepine and benzodioxathiepine derivatives | FBC LIMITED (GB) | 1980-02-06 | — | — | EP | disclosed |
| US-4183741-A | POSTEMERGENCE | FISONS LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4163846-A | HERBICIDES | FISONS LIMITED (GB) | 1979-08-07 | — | — | US | disclosed |
| US-4162154-A | BENZOFURAN DERIVATIVES | FISONS LIMITED (GB) | 1979-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190142010-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PTMS | KDM4E 1791/4885ALDH1A1 2204/4885SMN1; SMN2 2798/4885 |
| US-20150150253-A1 | CROP ENHANCEMENT COMPOSITIONS | ACHE, DDT, BCHE | KDM4E 93/4885ALDH1A1 4123/4885SMN1; SMN2 1904/4885 |
| US-10674728-B2 | Pesticidal compositions | ACHE, DDT, PTMS | KDM4E 1791/4885ALDH1A1 2204/4885SMN1; SMN2 2798/4885 |
| US-20050020677-A1 | Compounds having prolyl oligopeptidase inhibitory activity, methods for their preparation and their use | DNPEP, PREP, ANPEP | KDM4E 2621/4885ALDH1A1 827/4885SMN1; SMN2 2511/4885 |
| US-20150245610-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING CARBOXAMIDE DERIVATIVES | AADAC, PFAS, CBR3 | KDM4E 901/4885ALDH1A1 1326/4885SMN1; SMN2 4330/4885 |
| US-20190313646-A1 | INSECTICIDE MIXTURES COMPRISING LOLINE ALKALOIDS | ACHE, DDT, LARP7 | KDM4E 1794/4885ALDH1A1 1344/4885SMN1; SMN2 2934/4885 |
| US-20150189876-A1 | CROP ENHANCEMENT COMPOSITIONS | ACHE, DDT, BCHE | KDM4E 93/4885ALDH1A1 4123/4885SMN1; SMN2 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.