SCHEMBL26536393

SCHEMBL26536393

CC(C)(C)c1cc(-c2ccc3c(c2)[nH]c2c(Br)cc4c5ccccc5sc4c23)cc(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TNKS O95271 3/20 0.37
▸ TNKS2 Q9H2K2 3/20 0.37
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ HCRTR1 O43613 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ RAB9A P51151 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ KIF11 P52732 2/20 0.34
▸ MAP3K9 P80192 3/20 0.33
▸ MAP3K11 Q16584 3/20 0.33
▸ CDK4 P11802 1/20 0.33
▸ CCND1 P24385 1/20 0.33
▸ PTPN1 P18031 1/20 0.31
▸ NTRK1 P04629 1/20 0.31
▸ MAP3K10 Q02779 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26536401 0.90 TNKS2 (0.37) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536547 0.86 TNKS2 (0.34) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536387 0.86 KIF11 (0.41) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536418 0.86 TNKS2 (0.41) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536554 0.85 TNKS (0.34) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536550 0.84 KIF11 (0.34) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536395 0.81 TNKS (0.33) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL25201976 0.79 MEN1 (0.55) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536462 0.75 KIF11 (0.41) TNKSTNKS2MEN1KMT2AKDM4E
SCHEMBL26536414 0.70 CDK4 (0.49) TNKSTNKS2MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322802-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 — — US disclosed
US-20230322802-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322802-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE CRY1, LAGE3, CRY2 TNKS 1133/4885TNKS2 1405/4885MEN1 618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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