SCHEMBL265368

SCHEMBL265368

CCCCCCCCC=NO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
THRB P10828 1/20 0.42
EP300 Q09472 1/20 0.41
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 1/20 0.41
TERT O14746 3/20 0.40
MAPT P10636 2/20 0.40
BLM P54132 2/20 0.40
HSD17B10 Q99714 2/20 0.40
FABP4 P15090 2/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
APEX1 P27695 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267255 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL12335953 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL4890632 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL7596228 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL10496307 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL10496303 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL1921557 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
Heptanal Oxime SCHEMBL15257172 1.00
Heptanal Oxime SCHEMBL265491 1.00
SCHEMBL265367 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110964218-B Water-resistant PVA film and preparation method thereof 江门市新构思环保科技有限公司 2022-03-11 CN disclosed
EP-3365897-B1 USE OF ALDOXIMES COMPRISING AT LEAST 5 FIVE CARBON ATOMS AS ANTI-NITRIC AGENT IN REDUCTIVE PLUTONIUM BACK-EXTRACTION-OPERATIONS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2019-11-06 EP disclosed
EP-3365897-A1 USE OF ALDOXIMES COMPRISING AT LEAST FIVE CARBON ATOMS AS ANTI-NITROUS AGENTS IN OPERATIONS FOR THE REDUCTIVE BACK-EXTRACTION OF PLUTONIUM Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2018-08-29 EP disclosed
WO-2017067933-A1 USE OF ALDOXIMES COMPRISING AT LEAST FIVE CARBON ATOMS AS ANTI-NITROUS AGENTS IN OPERATIONS FOR THE REDUCTIVE BACK-EXTRACTION OF PLUTONIUM COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2017-04-27 WO disclosed
EP-1655070-B1 OXIDATION CATALYST ASAHI KASEI CHEMICALS CORP (JP) 2015-07-15 EP disclosed
WO-2015043473-A1 GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2015-04-02 WO disclosed
CN-103172482-B Method for preparing first-grade amide from aldoxime or formaldehyde and hydroxylamine UNIV WENZHOU 2015-02-18 CN disclosed
CN-103172482-A Method for preparing first-grade amide from aldoxime or formaldehyde and hydroxylamine UNIV WENZHOU 2013-06-26 CN disclosed
US-8133834-B2 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-13 US disclosed
CN-1835800-B Oxidation catalyst ASAHI CHEMICAL CORP (JP) 2010-04-28 CN disclosed
US-20100069670-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-03-18 US disclosed
US-20060229471-A1 Oxidation catalyst ASAHI KASEI CHEMICALS CORPORATION (JP) 2006-10-12 US disclosed
CN-1835800-A Oxidation catalyst ASAHI CHEMICAL CORP (JP) 2006-09-20 CN disclosed
EP-1655070-A1 OXIDATION CATALYST Asahi Kasei Chemicals Corporation (JP) 2006-05-10 EP disclosed
US-7025899-B2 Concentrated solutions of oxime metal extractants and method of formulating extractant compositions therefrom COGNIS CORPORATION (US) 2006-04-11 US disclosed
EP-0080700-B2 A process for producing nitrile compounds SUMITOMO CHEMICAL CO (JP) 1994-08-17 EP disclosed
EP-0080700-B1 A PROCESS FOR PRODUCING NITRILE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-04-23 EP disclosed
US-4456562-A AZEOTROPIC DISTILLATION OF WATER FROM REACTION PRODUCT OF ANALDEHYDE AND HYDROXYLAMINE OR ALDOXIME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-06-26 US disclosed
EP-0080700-A1 A process for producing nitrile compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-06-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069670-A1 Oxidation catalyst PPOX, SOD1, HAO2 TSHR 4696/4885THRB 4740/4885EP300 1250/4885
US-20060229471-A1 Oxidation catalyst PPOX, SOD1, HAO2 TSHR 4696/4885THRB 4740/4885EP300 1250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.