SCHEMBL4890632

SCHEMBL4890632

CCCCCCC/C=N/O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.52
THRB P10828 1/20 0.42
EP300 Q09472 1/20 0.41
FAAH O00519 3/20 0.41
TRPV1 Q8NER1 1/20 0.41
TERT O14746 3/20 0.40
MAPT P10636 2/20 0.40
BLM P54132 2/20 0.40
HSD17B10 Q99714 2/20 0.40
FABP4 P15090 2/20 0.40
GMNN O75496 1/20 0.40
USP2 O75604 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
APEX1 P27695 1/20 0.40
CYP2C19 P33261 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267255 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL12335953 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL7596228 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL10496307 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL10496303 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL1921557 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
SCHEMBL265368 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1
Heptanal Oxime SCHEMBL15257172 1.00
Heptanal Oxime SCHEMBL265491 1.00
SCHEMBL265367 1.00 TSHR (0.52) TSHRTHRBEP300FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023213381-A1 NOVEL FRAGRANCE COMPOUNDS SYMRISE AG (DE) 2023-11-09 WO claimed
EP-3723709-A1 PERFUME MIXTURES CONTAINING 8,8-DIMETHYL-6,10-DIOXASPIRO[4,5]DECANE Symrise AG (DE) 2020-10-21 EP claimed
US-4528167-A Selective solvent extraction using organophosphorus and carboxylic acids and a non-chelating aldehyde oxime COUNCIL FOR MINERAL TECHNOLOGY (ZA) 1985-07-09 US claimed
EP-4695016-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2026-02-18 EP disclosed
WO-2024213507-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-10-17 WO disclosed
US-12076436-B2 Bacterial ferment of Lactobacillus species SYMRISE AG (DE) 2024-09-03 US disclosed
WO-2023213381-A1 NOVEL FRAGRANCE COMPOUNDS SYMRISE AG (DE) 2023-11-09 WO disclosed
US-11753385-B2 Method for producing kakeromycin and derivatives thereof OP BIO FACTORY CO., LTD. (JP) 2023-09-12 US disclosed
US-11753385-B2 Method for producing kakeromycin and derivatives thereof OP BIO FACTORY CO., LTD. (JP) 2023-09-12 US disclosed
CN-115867541-A Aminopyrimidinone derivatives 豪夫迈·罗氏有限公司 2023-03-28 CN disclosed
US-20220354775-A1 NOVEL BACTERIAL FERMENT OF LACTOBACILLUS SPECIES SYMRISE AG (DE) 2022-11-10 US disclosed
US-20180037555-A1 METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF OP BIO FACTORY CO., LTD. (JP) 2018-02-08 US disclosed
WO-2017070131-A2 PARTICLES FOR MALODOR REDUCTION THE PROCTER & GAMBLE COMPANY (US) 2017-04-27 WO disclosed
EP-3131921-A1 POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2017-02-22 EP disclosed
EP-3117001-A1 POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novazymes A/S (DK) 2017-01-18 EP disclosed
WO-2015158237-A1 POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2015-10-22 WO disclosed
WO-2015135464-A1 POLYPEPTIDES WITH LIPASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2015-09-17 WO disclosed
US-7405318-B2 Method for producing nitriles by elimination of water from aldehyde oximes with alkylphosphonic anhydrides ARCHIMICA GMBH (DE) 2008-07-29 US disclosed
US-20080033186-A1 Method For Producing Nitriles By Elimination Of Water From Aldehyde Oximes With Alkylphosphonic Anhydrides EUTICALS GMBH (DE) 2008-02-07 US disclosed
US-4528167-A Selective solvent extraction using organophosphorus and carboxylic acids and a non-chelating aldehyde oxime COUNCIL FOR MINERAL TECHNOLOGY (ZA) 1985-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037555-A1 METHOD FOR PRODUCING KAKEROMYCIN AND DERIVATIVES THEREOF ERG28, CYP51A1, NISCH TSHR 3590/4885THRB 3888/4885EP300 2899/4885
US-11753385-B2 Method for producing kakeromycin and derivatives thereof ERG28, CYP51A1, NISCH TSHR 3590/4885THRB 3888/4885EP300 2899/4885
US-20080033186-A1 Method For Producing Nitriles By Elimination Of Water From Aldehyde Oximes With Alkylphosphonic Anhydrides NOX3, CA13, NOS3 TSHR 754/4885THRB 1812/4885EP300 1002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.