SCHEMBL26537109

SCHEMBL26537109

O=S(=O)(Nc1cc(Cl)ccc1C(F)(F)F)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.56
FBP1 P09467 1/20 0.56
CCR9 P51686 4/20 0.54
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
LMNA P02545 1/20 0.51
CCR2 P41597 10/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26537124 0.86 LMNA (0.62) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL26536592 0.85 LMNA (0.66) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL26537032 0.82 LMNA (0.77) FFAR4FBP1CCR9KMT2ALMNA
SCHEMBL26537147 0.81 CCR9 (0.53) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL26537094 0.81 SLC22A12 (0.57) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL26537047 0.79 LMNA (0.57) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL7570765 0.78 CES1 (0.67) FFAR4FBP1
SCHEMBL26537255 0.78 FFAR4 (0.57) FFAR4FBP1CCR9GAAKMT2A
SCHEMBL1471420 0.77 LMNA (0.68) KMT2ALMNACCR2
SCHEMBL26536553 0.77 FFAR4 (0.73) FFAR4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS YTHDF1, YTHDF3, YTHDF2 FFAR4 2391/4885FBP1 2982/4885CCR9 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.