SCHEMBL26537255

SCHEMBL26537255

O=S(=O)(Nc1ccc(F)cc1C(F)(F)F)c1ccc(OC(F)(F)F)cc1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.57
GAA P10253 1/20 0.52
KMT2A Q03164 1/20 0.52
CCR9 P51686 5/20 0.50
HSD11B1 P28845 1/20 0.47
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
SLC22A12 Q96S37 1/20 0.43
FBP1 P09467 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595506 0.88 FFAR4 (0.57) FFAR4CCR9KEAP1NFE2L2FBP1
SCHEMBL26530288 0.82 FFAR4 (0.54) FFAR4GAAKMT2ACCR9
SCHEMBL26536602 0.82 WDR5 (0.56) FFAR4GAAKMT2ACCR9
SCHEMBL7573010 0.81 FFAR4 (0.52) FFAR4CCR9KEAP1NFE2L2
SCHEMBL9321921 0.79 PTPN1 (0.54) FFAR4KMT2A
SCHEMBL26537109 0.78 FFAR4 (0.56) FFAR4GAAKMT2ACCR9FBP1
SCHEMBL7570513 0.77 FFAR4 (0.64) FFAR4
SCHEMBL5597750 0.76 FFAR4 (0.53) FFAR4CCR9FBP1
SCHEMBL7590053 0.76 FFAR4 (0.59) FFAR4GAAKMT2ACCR9FBP1
SCHEMBL7569763 0.76 FFAR4 (0.59) FFAR4GAAKMT2ACCR9FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230322715-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS YTHDF1, YTHDF3, YTHDF2 FFAR4 2391/4885GAA 1944/4885KMT2A 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.