SCHEMBL26537156

SCHEMBL26537156

Cc1ccccc1N1c2cncnc2N(N)C1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.36
CYP3A4 P08684 5/20 0.36
CYP2D6 P10635 5/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 2/20 0.36
RECQL P46063 1/20 0.36
RPS6KB1 P23443 1/20 0.36
PI4KA P42356 1/20 0.33
PI4K2B Q8TCG2 1/20 0.33
PI4K2A Q9BTU6 1/20 0.33
PI4KB Q9UBF8 1/20 0.33
HSD17B10 Q99714 1/20 0.31
FLT3 P36888 1/20 0.31
GSK3B P49841 1/20 0.31
OPRM1 P35372 1/20 0.30
SLC9A1 P19634 1/20 0.30
SLC2A1 P11166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23256061 0.89 CYP1A2 (0.36) CYP1A2CYP3A4CYP2D6MEN1KMT2A
SCHEMBL22747679 0.84 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6MEN1KMT2A
SCHEMBL26248804 0.82 CYP1A2 (0.36) CYP1A2CYP3A4CYP2D6MEN1KMT2A
SCHEMBL23255824 0.81 NOS3 (0.37) MEN1KMT2AALDH1A1TSHRPI4KA
SCHEMBL19228755 0.80 CYP1A2 (0.36) CYP1A2CYP3A4CYP2D6MEN1KMT2A
SCHEMBL23255823 0.77 PI4KA (0.35) KMT2AALDH1A1TSHRPI4KAPI4K2B
SCHEMBL23636182 0.75 ALDH1A1 (0.37) MEN1KMT2AALDH1A1TSHRHSD17B10
SCHEMBL24845002 0.73 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6MEN1KMT2A
SCHEMBL23636183 0.72 NOS3 (0.37) MEN1KMT2AALDH1A1TSHRPI4KA
SCHEMBL24981453 0.70 CYP1A2 (0.40) CYP1A2CYP3A4CYP2D6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230138288-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, RUVBL2, LBR CYP1A2 515/4885CYP3A4 1901/4885CYP2D6 916/4885
US-20230371358-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, SOD1, ROS1 CYP1A2 2458/4885CYP3A4 2401/4885CYP2D6 3917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.