Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19243050 | 0.83 | NOTUM (0.40) | KMT2ANOTUM | |
| SCHEMBL19586524 | 0.78 | KDM4E (0.41) | — | |
| SCHEMBL24169816 | 0.75 | PBRM1 (0.39) | KMT2AMAPTCYP2C9HTT | |
| SCHEMBL6561465 | 0.67 | — | — | |
| SCHEMBL7586830 | 0.67 | ALDH1A1 (0.42) | KMT2AMAPTNOTUM | |
| SCHEMBL17372113 | 0.64 | KDM4E (0.37) | KMT2AMAPTCYP2C9 | |
| SCHEMBL221825 | 0.64 | SLC9A1 (0.41) | KMT2AMAPTCYP2C9NOTUMCRBN | |
| SCHEMBL4284402 | 0.63 | NR4A2 (0.44) | — | |
| SCHEMBL27698036 | 0.63 | PBRM1 (0.39) | KMT2AMAPTCYP2C9HTT | |
| SCHEMBL17351674 | 0.60 | ADORA2A (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49700-E1 | Substituted nitrogen containing compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-17 | — | — | US | disclosed |