Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30341043 | 0.98 | SIGMAR1 (0.35) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL14584234 | 0.84 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL27141666 | 0.82 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL92632 | 0.82 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL29165085 | 0.80 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL27142082 | 0.79 | USP2 (0.41) | ALDH1A1HTTSMN1; SMN2CHRM3 | |
| SCHEMBL16211550 | 0.78 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL16935402 | 0.77 | POLB (0.35) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL2102695 | 0.77 | POLB (0.38) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB | |
| SCHEMBL5652 | 0.77 | POLB (0.38) | SIGMAR1ALDH1A1HTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-07-04 | — | — | US | disclosed |
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-07-04 | — | — | US | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| CN-104364246-B | Piperidine derivatives useful as GPR119 agonists | 株式会社钟根堂 | 2018-05-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | HBZ, ZFX, WIZ | SIGMAR1 2433/4885ALDH1A1 1243/4885HTT 2340/4885 |
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | ADORA2A, ADORA1, ADORA2B | SIGMAR1 457/4885ALDH1A1 368/4885HTT 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.