Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27754818 | 0.98 | SLC6A2 (0.33) | SLC6A2SLC6A4CYP2D6ANPEPHTR2A | |
| SCHEMBL29954879 | 0.81 | ALDH1A1 (0.44) | CYP2D6RAB9ASMN1; SMN2LMNAACP3 | |
| SCHEMBL96452 | 0.81 | ALDH1A1 (0.44) | CYP2D6RAB9ASMN1; SMN2LMNAACP3 | |
| SCHEMBL28612853 | 0.80 | PRCP (0.37) | SLC6A2SLC6A4CYP2D6HTR2ANPC1 | |
| SCHEMBL9113377 | 0.78 | SLC6A2 (0.33) | SLC6A2SLC6A4CYP2D6HTR2ANPC1 | |
| SCHEMBL7993927 | 0.76 | MAOB (0.33) | HTR2ASMN1; SMN2MAOAMAOB | |
| SCHEMBL29262239 | 0.74 | PDE4A (0.43) | NPC1MAOAMAOB | |
| SCHEMBL28769668 | 0.74 | MAOA (0.40) | NPC1RAB9ASMN1; SMN2NISCHMAOA | |
| SCHEMBL27745499 | 0.74 | ACHE (0.34) | SLC6A2SLC6A4CYP2D6HTR2ASLC6A3 | |
| SCHEMBL27491263 | 0.74 | KDM1A (0.36) | SLC6A2SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173899-B | Synthesis method of isobenzofuran-1 (3H) -ketone compound | 都创(上海)医药科技股份有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-117186045-A | Isobenzofuran-1 (3H) -ketone TREK-1 inhibitor, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-12-08 | — | — | CN | claimed |
| CN-116535397-A | Isobenzofuran-1 (3H) -one compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-08-04 | — | — | CN | claimed |
| CN-113173899-A | Method for synthesizing isobenzofuran-1 (3H) -ketone compound | 都创(上海)医药科技股份有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-104004019-A | Pyrimidine-containing organic phosphorus compound and application thereof | SHANDONG UNITED PESTICIDE INDUSTRY CO LTD | 2014-08-27 | — | — | CN | claimed |
| CN-101663309-B | Process for preparing substituted pentacenes | MERCK PATENT GMBH | 2013-08-14 | — | — | CN | claimed |
| CN-103083311-A | Pharmaceutical composition of 3-butyl-3H-2-benzofuran-1-one and preparation method thereof | XU JI | 2013-05-08 | — | — | CN | claimed |
| CN-102491886-A | Method for synthetizing indanone compound | SHANGHAI RES INST CHEMICAL IND | 2012-06-13 | — | — | CN | claimed |
| CN-101595386-B | Method for detecting phenothiazine-derivative color, and color-developer reagent used in method | ARKRAY INC | 2012-05-09 | — | — | CN | claimed |
| CN-101663309-A | Process for preparing substituted pentacenes | MERCK PATENT GMBH | 2010-03-03 | — | — | CN | claimed |
| CN-101595386-A | The detection method of phenothiazine derivative pigment and be used for the color-developer reagent of this method | ARKRAY INC (JP) | 2009-12-02 | — | — | CN | claimed |
| CN-1914173-A | Quinolines useful in treating cardiovascular disease | WYETH CORP (US) | 2007-02-14 | — | — | CN | claimed |
| CN-113173899-B | Synthesis method of isobenzofuran-1 (3H) -ketone compound | 都创(上海)医药科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-113173899-B | Synthesis method of isobenzofuran-1 (3H) -ketone compound | 都创(上海)医药科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186045-A | Isobenzofuran-1 (3H) -ketone TREK-1 inhibitor, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-12-08 | — | — | CN | disclosed |
| CN-117186045-A | Isobenzofuran-1 (3H) -ketone TREK-1 inhibitor, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-12-08 | — | — | CN | disclosed |
| CN-1308071-A | Bicyclic DNA gyrase inhibitor | HOFFMANN LA ROCHE (CH) | 2001-08-15 | — | — | CN | disclosed |
| CN-1279678-A | Method for producing phthalides | BASF AG (DE) | 2001-01-10 | — | — | CN | disclosed |
| CN-1114648-A | Novel monocyclic and bicyclic DNA gyrase inhibitors | HOFFMANN LA ROCHE (CH) | 1996-01-10 | — | — | CN | disclosed |
| CN-1089264-A | Derivatives of isobenzofaranone | GLAXO GROUP LTD (GB) | 1994-07-13 | — | — | CN | disclosed |